Febrifugal and SARS medicines - whether are dangerous they to a stomach?

In the everyday life we often use nonsteroid anti-inflammatory medicines which treat aspirin, diclofenac, paracetamol, an ibuprofen, nayz, etc. They reduce temperature, reduce signs of inflammation (so eliminate pain, at least for a while). They are well familiar and to the people having radiculitis. If to count all aspirin which is taken having coronary heart disease then the number of packs much more will exceed 100 million a year. Well nonsteroid anti-inflammatory medicines help us and at a SARS: though they do not render any effect on viruses, nevertheless, substantially level symptoms of a catarrhal disease (they are the main component of various "ferveks" and "koldreks"). Thus, medicines very much help us and are some of the most demanded. However, as always there is "a medal back". What needs to be known and what we have to be afraid of when we have to use nonsteroid anti-inflammatory medicines?

First of all medicines are known for the side effects on the digestive tract (DT). Reducing expressiveness of inflammatory changes, they in parallel reduce the resilience of a mucous membrane of a stomach and intestines to aggression factors (gastric juice, organic acids, etc.) that is of particular importance at a SARS when we "escape" high doses of ascorbic acid, fruit drinks, etc. Even worse the situation when long administration of drugs is necessary is: arthritises, radiculitises, injuries. Against the background of long reception there is a gastropatiya – the diffusion damage of a mucous membrane of a stomach caused by sharp decrease in its resilience against the background of use of nonsteroid anti-inflammatory medicines (NPVP). Result: every third patient accepting "cardioaspirin" (or as it is correct to call it low-dose) has NPVP – the associated gastropatiya; a third of all patients coming to hospitals with gastrointestinal bleedings are an accepting NPVP; from them 13-15% had lethal an outcome (statistics, over the countries of Europe and North America).

Certainly much attention is paid to this problem by rheumatologists (as doctors of this specialty have experience of long purpose of NPVP), gastroenterologists and therapists (doctors who should treat NPVP – the associated gastropatiya). For the purpose of prevention and treatment of defeats of a stomach sekretolitichesky medicines are appointed mucous doctors. However medicines of this group have an impact only on "the top floors" of a GIT: stomach, duodenum. Thus, the mucous membrane of a small and thick intestine remains without protection when using NPVP. Considerable length (about 6 meters) and the huge area (nearly 2 tennis courts) of intestines predetermines a possibility of massive blood loss even at insignificant erosive damage of a mucous membrane. Rather recently patients had an opportunity to change this situation: new medicine was registered rebagit, strengthening a reparation (restoration) of a mucous membrane not only stomach, but also intestines. However this fact does not relieve all completeness responsibility from patients, is long the accepting NPVP: accurate justification of purpose of medicines and control of safety of reception is necessary. In case of symptoms of gastrointestinal bleeding (noise in ears, dizziness, weakness, cold sweat, heartbeat, falling HELL, a faint) such patients are recommended to ask for emergency medical service immediately.

And still. Remember that the scheme of treatment appointed by the doctor should not change or be corrected by the patient independently at all. Each medicine which is picked up by the doctor is an important component of the general scheme of treatment in your case and cannot be replaced with other medicine even if it seems to you that in it there is nothing terrible, and the druggist assures of drugstore that other medicine better or is not worse than that in your recipe at all. Especially you should not cancel independently even one of the medicines appointed by the doctor. It not only will reduce efficiency of therapy, but also can be dangerous.

Sas Evgeny Ivanovich is a gastroenterologist, the hepatologist, the doctor of medical sciences, professor, the leading researcher of research center of the St. Petersburg state pediatric medical university.